Journal article Closed Access

Metadoxine in the treatment of acute and chronic alcoholism: a review.

Giovanni Gasbarrini; Esmeralda Capristo; Giovanni Addolorato; C. Ancona


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  <identifier identifierType="URL">https://www.openaccessrepository.it/record/107253</identifier>
  <creators>
    <creator>
      <creatorName>Giovanni Gasbarrini</creatorName>
    </creator>
    <creator>
      <creatorName>Esmeralda Capristo</creatorName>
    </creator>
    <creator>
      <creatorName>Giovanni Addolorato</creatorName>
    </creator>
    <creator>
      <creatorName>C. Ancona</creatorName>
    </creator>
  </creators>
  <titles>
    <title>Metadoxine in the treatment of acute and chronic alcoholism: a review.</title>
  </titles>
  <publisher>INFN Open Access Repository</publisher>
  <publicationYear>2003</publicationYear>
  <subjects>
    <subject>Pharmacology</subject>
    <subject>Immunology</subject>
    <subject>Immunology and Allergy</subject>
    <subject>Pharmacology</subject>
    <subject>Immunology</subject>
    <subject>Immunology and Allergy</subject>
  </subjects>
  <dates>
    <date dateType="Issued">2003-09-01</date>
  </dates>
  <language>en</language>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://www.openaccessrepository.it/record/107253</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1177/039463200301600304</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="URL" relationType="IsPartOf">https://www.openaccessrepository.it/communities/itmirror</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="info:eu-repo/semantics/closedAccess">Closed Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Alcohol abuse and alcoholism are responsible for a wide variety of medical problems. The pharmacotherapeutic aspect of alcoholism includes the use of drugs, with different actions and objectives. Among them, metadoxine seems to be of interest. Metadoxine is able to accelerate the elimination of alcohol from the blood and tissues, to help restore the functional structure of the liver and to relieve neuro-psychological disorders associated with alcohol intoxication. Metadoxine also seems to be safe; in more than 15 years of post-marketing surveillance only minor aspecific and reversible events were monitored in patients exposed to the treatment. In this review the preclinical and clinical results obtained using metadoxine in acute and chronic alcohol intoxication are reported.</description>
  </descriptions>
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